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ACCUTANE (ISOTRETINOIN) CAPSULES: MEDICATION GUIDE - HOW TO TAKE

How should I take Accutane (Isotretinoin) pills?

  • You must take Accutane exactly as prescribed. You must also follow all the instructions of the iPLEDGE program. Before prescribing Isotretinoin (Accutane) pills, your doctor will:

    - explain the iPLEDGE program to you
    - have you sign the Patient Information/Informed Consent (for all patients). Female patients who can get pregnant must also sign another consent form.

    You will not be prescribed Accutane if you cannot agree to or follow all the instructions of the iPLEDGE program.

  • You will get no more than a 30-day supply of Accutane (Isotretinoin) at a time. This is to make sure you are following the Accutane iPLEDGE program. You should talk with your doctor each month about side effects.
  • The amount of this medication you take has been specially chosen for you. It is based on your body weight, and may change during treatment.
  • Take Accutane 2 times a day with a meal, unless your doctor tells you otherwise. Swallow your Accutane capsules whole with a full glass of liquid. Do not chew or suck on the capsule. Isotretinoin (Accutane) can hurt the tube that connects your mouth to your stomach (esophagus) if it is not swallowed whole.
  • If you miss a dose, just skip that dose. Do not take 2 doses at the same time.
  • If you take too much Accutane or overdose, call your doctor or poison control center right away.
  • Your acne may get worse when you first start taking Accutane. This should last only a short while. Talk with your doctor if this is a problem for you.
  • You must return to your doctor as directed to make sure you don't have signs of serious side effects. Your doctor may do blood tests to check for serious side effects from Accutane. Female patients who can get pregnant will get a pregnancy test each month.
  • Female patients who can get pregnant must agree to use 2 separate forms of effective birth control at the same time 1 month before, while taking, and for 1 month after taking Accutane (Isotretinoin) capsules. You must access the iPLEDGE system to answer questions about the program requirements and to enter your 2 chosen forms of birth control.

    You must talk about effective birth control methods with your healthcare provider or go for a free visit to talk about birth control with another doctor or family planning expert. Your doctor can arrange this free visit, which will be paid for by the company that makes Accutane.

    If you have sex at any time without using 2 forms of effective birth control, get pregnant, or miss your expected period, stop using Accutane and call your doctor right away.

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